Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.61 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867662 | 0.87 | HSP90AA1 (0.68) | HIF1AHSP90AA1HIF1AN | |
| SCHEMBL18245316 | 0.79 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL16867663 | 0.78 | HIF1A (0.81) | HIF1AHSP90AA1 | |
| SCHEMBL31376270 | 0.77 | ACHE (1.00) | ACHEHIF1AN | |
| SCHEMBL16865541 | 0.77 | HSP90AA1 (0.78) | HIF1AHSP90AA1HIF1AN | |
| SCHEMBL31074345 | 0.76 | ACHE (0.59) | HIF1AACHEHSP90AA1HIF1AN | |
| SCHEMBL18597480 | 0.75 | HIF1A (0.53) | HIF1AHSP90AA1 | |
| SCHEMBL18244956 | 0.72 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL18597476 | 0.72 | HSP90AA1 (0.49) | HIF1AHSP90AA1HIF1AN | |
| SCHEMBL28836658 | 0.71 | HIF1A (0.56) | HIF1AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475347-A | Combinations of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and norepinephrine reuptake inhibitors for the treatment of sleep apnea | 拜耳公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118541153-A | Conjugates of a TASK1/3 channel blocker and a norepinephrine reuptake inhibitor for the treatment of sleep apnea | 拜耳公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-118384147-A | Methods and compositions for treating sleep apnea | 爱普宁公司(特拉华) | 2024-07-26 | — | — | CN | disclosed |
| CN-117396460-A | Solid forms of (R) -oxybutynin D-malate | 爱普宁公司(特拉华) | 2024-01-12 | — | — | CN | disclosed |