Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747511 | 0.81 | DGAT1 (0.50) | DGAT1CA1 | |
| SCHEMBL27820854 | 0.80 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL8837534 | 0.78 | — | — | |
| SCHEMBL28303089 | 0.77 | FAAH (0.47) | — | |
| SCHEMBL27328998 | 0.77 | DGAT1 (0.54) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL20503363 | 0.76 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL1486198 | 0.75 | DGAT1 (0.44) | DGAT1CA1 | |
| SCHEMBL28714854 | 0.75 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL29908023 | 0.75 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL27859821 | 0.75 | DGAT1 (0.44) | DGAT1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170489-B | New Pyrazolopyrimidine derivative and its purposes as MALT1 inhibitor | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-106170489-A | New Pyrazolopyrimidine derivative and the purposes as MALT1 inhibitor thereof | 诺华股份有限公司 | 2016-11-30 | — | — | CN | disclosed |