SCHEMBL28836967

SCHEMBL28836967

CNC(=O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PYGM P11217 3/20 0.62
▸ TK2 O00142 2/20 0.57
▸ SLC28A1 O00337 1/20 0.53
▸ SLC28A2 O43868 1/20 0.53
▸ SLC29A1 Q99808 1/20 0.53
▸ SLC28A3 Q9HAS3 1/20 0.53
▸ P2RY2 P41231 4/20 0.50
▸ DNPH1 O43598 1/20 0.49
▸ TYMP P19971 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25824050 0.91 PYGM (0.50) PYGMTK2P2RY2DNPH1
SCHEMBL25241091 0.87 PYGM (0.66) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL15526515 0.87 PYGM (0.66) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2587057 0.87 PYGM (0.66) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL16974934 0.87 PYGM (0.69) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL16974933 0.87 PYGM (0.69) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL31059434 0.86 PYGM (0.62) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL15297978 0.86 PYGM (0.68) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL15297980 0.85 PYGM (0.65) PYGMTK2SLC28A1SLC28A2SLC29A1
Water SCHEMBL28305672 0.85 PYGM (0.61) PYGMTK2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115023503-A Method for producing closed linear DNA 泰瑞斯疗法公司 2022-09-06 — — CN disclosed
CN-115003829-A Closed linear DNA with modified nucleotides 泰瑞斯疗法公司 2022-09-02 — — CN disclosed
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