Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.48 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.47 |
| ▸ | TK2 | O00142 | 2/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836967 | 0.91 | PYGM (0.62) | PYGMP2RY2DNPH1TK2 | |
| SCHEMBL25824045 | 0.85 | P2RY2 (0.48) | PYGMP2RY2DNPH1TK2P2RY6 | |
| SCHEMBL25824048 | 0.83 | TK2 (0.41) | PYGMDNPH1TK2 | |
| SCHEMBL19272148 | 0.80 | PYGM (0.56) | PYGMP2RY2DNPH1TK2P2RY6 | |
| SCHEMBL16923193 | 0.80 | PYGM (0.56) | PYGMP2RY2TK2LMNA | |
| SCHEMBL10226146 | 0.80 | PYGM (0.56) | PYGMP2RY2TK2LMNA | |
| SCHEMBL25824058 | 0.80 | TK1 (0.54) | TK2LMNASMN1; SMN2 | |
| SCHEMBL13694991 | 0.79 | LMNA (0.70) | PYGMP2RY2DNPH1TK2P2RY6 | |
| SCHEMBL15482194 | 0.79 | LMNA (0.70) | PYGMP2RY2DNPH1TK2P2RY6 | |
| SCHEMBL13650210 | 0.79 | LMNA (0.70) | PYGMP2RY2DNPH1TK2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |