SCHEMBL2883698

SCHEMBL2883698

Cc1c(NS(C)(=O)=O)ccc2c1OC(C)(C)C(O)C2NCCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.43
KCNA5 P22460 6/20 0.42
NR3C1 P04150 8/20 0.41
PGR P06401 1/20 0.41
NR3C2 P08235 1/20 0.41
AR P10275 1/20 0.41
ABCB1 P08183 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2883701 1.00 IDO1 (0.43) IDO1KCNA5NR3C1PGRNR3C2
SCHEMBL2891648 0.84 NAAA (0.39) IDO1KCNA5NR3C1
SCHEMBL2891644 0.82 KCNA5 (0.42) KCNA5NR3C1PGRNR3C2AR
SCHEMBL2887648 0.82 KCNA5 (0.50) IDO1KCNA5ABCB1
SCHEMBL2889459 0.80 KCNA5 (0.47) IDO1KCNA5NR3C1ABCB1
SCHEMBL2889241 0.80 ALDH1A1 (0.42) IDO1KCNA5ABCB1
SCHEMBL5987814 0.80 ALDH1A1 (0.42) IDO1KCNA5ABCB1
SCHEMBL2889239 0.80 ALDH1A1 (0.42) IDO1KCNA5ABCB1
SCHEMBL2889456 0.80 KCNA5 (0.47) IDO1KCNA5NR3C1ABCB1
SCHEMBL2883998 0.80 KCNA5 (0.48) IDO1KCNA5ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1718629-B1 Benzopyran compounds useful for the treatment of arrhytmia NISSAN CHEMICAL IND LTD (JP) 2012-12-26 EP claimed
US-20070299130-A1 Benzopyran Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-12-27 US claimed
US-7781483-B2 Benzopyran compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-08-24 US disclosed
US-20070299130-A1 Benzopyran Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299130-A1 Benzopyran Compound NR0B1, CYP2B6, RYR2 IDO1 2825/4885KCNA5 69/4885NR3C1 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.