Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116650 | 0.86 | BCL2 (0.56) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8021478 | 0.81 | KDM4E (0.70) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8024179 | 0.80 | KDM4E (0.58) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8024166 | 0.78 | KDM4E (0.56) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8010677 | 0.78 | KDM4E (0.56) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8021964 | 0.78 | TP53 (0.66) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8023335 | 0.78 | KDM4E (0.56) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8021582 | 0.78 | ALDH1A1 (0.67) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8023384 | 0.76 | KDM4E (0.69) | KDM4EGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL8023183 | 0.76 | NPSR1 (0.57) | KDM4EGAAMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |