Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837340 | 0.86 | KDM4E (0.57) | BCL2MCL1TP53MAPTGAA | |
| SCHEMBL28116277 | 0.81 | NPC1 (0.60) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28116275 | 0.77 | ALDH1A1 (0.71) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10292364 | 0.77 | LMNA (0.53) | BCL2MCL1MAPTGAAALDH1A1 | |
| SCHEMBL28116654 | 0.76 | TP53 (0.71) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28116293 | 0.74 | MAPT (0.75) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28377758 | 0.72 | TP53 (0.84) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL24141126 | 0.70 | KDM4E (0.72) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL25876977 | 0.67 | KDM4E (0.67) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11324202 | 0.67 | ALDH1A1 (0.58) | TP53MAPTSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | claimed |
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |