SCHEMBL28837366

SCHEMBL28837366

CCc1c(C)ccc(C)c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 4/20 0.50
NOS3 P29474 3/20 0.50
POLB P06746 2/20 0.44
KDM4E B2RXH2 3/20 0.42
CD44 P16070 1/20 0.39
ALDH1A1 P00352 6/20 0.35
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ATP4A P20648 1/20 0.35
ATP4B P51164 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
CASP1 P29466 1/20 0.33
CYP3A4 P08684 2/20 0.32
TSHR P16473 2/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL982159 0.85 NOS2 (0.47) NOS2NOS3POLBKDM4ECD44
SCHEMBL6356384 0.85 NOS3 (0.42) NOS2NOS3POLBKDM4ECD44
Hydrochloric Acid SCHEMBL7256311 0.83 NOS2 (0.45) NOS2NOS3POLBKDM4ECD44
SCHEMBL8443799 0.83 NOS2 (0.45) NOS2NOS3POLBKDM4ECD44
SCHEMBL5697401 0.83 NOS3 (0.41) NOS2NOS3POLBKDM4ECD44
SCHEMBL426234 0.81 NOS2 (0.44) NOS2NOS3POLBKDM4EALDH1A1
SCHEMBL2423001 0.81 NOS3 (0.44) NOS2NOS3POLBKDM4EALDH1A1
SCHEMBL10341195 0.81 CYP3A4 (0.40) NOS2NOS3POLBKDM4ECD44
SCHEMBL17889885 0.81 NOS3 (0.39) NOS2NOS3POLBKDM4ECD44
SCHEMBL19412656 0.80 NOS2 (0.48) NOS2NOS3POLBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114729127-A Weather-resistant and durable coating composition 陶氏环球技术有限责任公司 2022-07-08 CN disclosed