Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593252 | 0.98 | DYRK1A (0.49) | DYRK1AALDH1A1KMT2AMEN1GAA | |
| SCHEMBL29941475 | 0.98 | DYRK1A (0.49) | DYRK1AALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8076216 | 0.82 | DYRK1A (0.60) | DYRK1AALDH1A1KMT2AMEN1GAA | |
| SCHEMBL1586683 | 0.81 | DYRK1A (0.49) | DYRK1AALDH1A1KMT2AMEN1GAA | |
| SCHEMBL27682808 | 0.79 | NPC1 (0.40) | DYRK1AALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9222743 | 0.78 | DYRK1A (0.55) | DYRK1APIK3CD | |
| SCHEMBL24155753 | 0.77 | CYP2A6 (0.41) | DYRK1AALDH1A1KMT2AMEN1GAA | |
| SCHEMBL14920274 | 0.77 | DYRK1A (0.47) | DYRK1AALDH1A1KMT2AMEN1GAA | |
| SCHEMBL26450316 | 0.77 | AHR (0.54) | DYRK1AALDH1A1KMT2AMEN1GAA | |
| SCHEMBL26450242 | 0.77 | AHR (0.54) | DYRK1AALDH1A1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890952-B | Preparation method of 5-halogeno-2-aminobenzoazacyclic compound | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-114890952-A | Preparation method of 5-halogenated-2-aminobenzene nitrogen heterocyclic compound | 重庆医科大学 | 2022-08-12 | — | — | CN | disclosed |