SCHEMBL8076216

SCHEMBL8076216

Clc1ccc(-c2ccc3ocnc3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 3/20 0.60
PIK3CD O00329 1/20 0.46
FASN P49327 1/20 0.44
GAA P10253 2/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42
TRPM5 Q9NZQ8 1/20 0.40
NOTUM Q6P988 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CTNNB1 P35222 1/20 0.39
WNT3A P56704 1/20 0.39
BACE1 P56817 1/20 0.39
ALOX5 P09917 1/20 0.38
FABP4 P15090 1/20 0.37
SCN9A Q15858 1/20 0.36
AHR P35869 1/20 0.36
CLK1 P49759 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28048555 0.88 DYRK1A (0.72) DYRK1APIK3CDFASNGAAMEN1
SCHEMBL24156066 0.85 DYRK1A (0.60) DYRK1APIK3CDGAANOTUMNPC1
SCHEMBL16457921 0.85 DYRK1A (0.49) DYRK1APIK3CDGAAMEN1ALDH1A1
SCHEMBL9222743 0.84 DYRK1A (0.55) DYRK1APIK3CDNOTUMBACE1ALOX5
SCHEMBL29941475 0.84 DYRK1A (0.49) DYRK1APIK3CDGAAMEN1ALDH1A1
SCHEMBL593252 0.84 DYRK1A (0.49) DYRK1APIK3CDGAAMEN1ALDH1A1
SCHEMBL592989 0.83 DYRK1A (0.62) DYRK1APIK3CDFASNGAAMEN1
SCHEMBL29375136 0.83 DYRK1A (0.62) DYRK1APIK3CDFASNGAAMEN1
Ammonia Solution, Strong SCHEMBL28837684 0.82 DYRK1A (0.47) DYRK1APIK3CDGAAMEN1ALDH1A1
SCHEMBL8080835 0.81 DYRK1A (0.60) DYRK1APIK3CDFASNGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5439789-A Support having atleast one light sensitive silver halide emulsion layer and methine dye having benzoxazole nucleus with a halogen substituted benzene ring at 5-position FUJI PHOTO FILM CO., LTD. (JP) 1995-08-08 US claimed
WO-2021261851-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-12-30 WO disclosed
EP-0625726-B1 Methine compound and silver halide photographic material comprising the same FUJI PHOTO FILM CO LTD (JP) 2000-08-09 EP disclosed
US-5439789-A Support having atleast one light sensitive silver halide emulsion layer and methine dye having benzoxazole nucleus with a halogen substituted benzene ring at 5-position FUJI PHOTO FILM CO., LTD. (JP) 1995-08-08 US disclosed
EP-0625726-A1 Methine compound and silver halide photographic material comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1994-11-23 EP disclosed