Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.38 |
| ▸ | WNT3A | P56704 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27663253 | 0.89 | SMN1; SMN2 (0.38) | NPC1MAPTMEN1KMT2AGAA | |
| SCHEMBL29941475 | 0.81 | DYRK1A (0.49) | NPC1MAPTMEN1KMT2AGAA | |
| SCHEMBL593252 | 0.81 | DYRK1A (0.49) | NPC1MAPTMEN1KMT2AGAA | |
| Benzo[D]Oxazole SCHEMBL27663185 | 0.80 | NPC1 (0.36) | NPC1MAPTMEN1KMT2AGAA | |
| Ammonia Solution, Strong SCHEMBL28837684 | 0.79 | DYRK1A (0.47) | NPC1MAPTMEN1KMT2AGAA | |
| SCHEMBL9150108 | 0.70 | DYRK1A (0.54) | NPC1MAPTMEN1KMT2AGAA | |
| SCHEMBL14920274 | 0.70 | DYRK1A (0.47) | NPC1MAPTMEN1KMT2AGAA | |
| SCHEMBL8076216 | 0.68 | DYRK1A (0.60) | NPC1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL9222743 | 0.68 | DYRK1A (0.55) | DYRK1A | |
| SCHEMBL926781 | 0.67 | ALDH1A1 (0.51) | NPC1MEN1KMT2AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296925-A | Novel benzopyran derivatives as potassium channel openers | JANSSEN PHARMACEUTICA NV (BE) | 2008-10-29 | — | — | CN | disclosed |
| CN-101296731-A | Novel benzopyran derivatives as potassium channel openers | JANSSEN PHARMACEUTICA NV (BE) | 2008-10-29 | — | — | CN | disclosed |
| CN-1993326-A | Heterocyclic acetophenone potentiators of metabotropic glutamate receptors | MERCK & CO INC (US) | 2007-07-04 | — | — | CN | disclosed |