SCHEMBL2883801

SCHEMBL2883801

Oc1c(Cc2ccccc2)cc(C2(c3cc(Cc4ccccc4)c(O)c(Cc4ccccc4)c3)c3ccccc3-c3ccccc32)cc1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 2/20 0.46
BCL2L1 Q07817 1/20 0.46
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
PTPN1 P18031 3/20 0.43
PTPN2 P17706 1/20 0.43
PTPN6 P29350 1/20 0.43
PDK2 Q15119 1/20 0.42
ALOX5 P09917 1/20 0.41
ELANE P08246 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
OPRK1 P41145 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19038925 0.91 KEAP1 (0.45) BCL2BCL2L1ESR1ESR2PTPN1
SCHEMBL20752931 0.90 PTPN1 (0.43) BCL2BCL2L1ESR1ESR2PTPN1
SCHEMBL21360617 0.85 ESR1 (0.47) BCL2BCL2L1ESR1ESR2PDK2
SCHEMBL2883692 0.84 ESR1 (0.56) BCL2BCL2L1ESR1ESR2PDK2
SCHEMBL29616930 0.84 ESR1 (0.56) BCL2BCL2L1ESR1ESR2PDK2
SCHEMBL10051848 0.81 ESR1 (0.47) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL900106 0.81 ESR1 (0.51) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL383389 0.79 PDK2 (0.40) BCL2BCL2L1ESR1ESR2PDK2
SCHEMBL2883963 0.77 ESR1 (0.47) ESR1ESR2PDK2ALOX5ELANE
SCHEMBL19038946 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781540-B2 Resin composition and molded articles thereof OSAKA GAS CO., LTD. (JP) 2010-08-24 US disclosed
US-7772356-B2 Infrared absorption filter OSAKA GAS CO., LTD. (JP) 2010-08-10 US disclosed
EP-1808461-B1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF TEIJIN CHEMICALS LTD (JP) 2009-03-11 EP disclosed
US-20080085955-A1 Resin Composition And Molded Articles Thereof OSAKA GAS CO., LTD. (JP) 2008-04-10 US disclosed
US-20070293606-A1 Infrared Absorption Filter OSAKA GAS CO., LTD. (JP) 2007-12-20 US disclosed
EP-1808461-A1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF Teijin Chemicals, Ltd. (JP) 2007-07-18 EP disclosed
EP-1804093-A1 INFRARED ABSORBING FILTER OSAKA GAS CO., LTD. (JP) 2007-07-04 EP disclosed