SCHEMBL2883963

SCHEMBL2883963

CCCc1cc(C2(c3cc(CCC)c(O)c(CCC)c3)c3ccccc3-c3ccccc32)cc(CCC)c1O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
PDK2 Q15119 8/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
OPRK1 P41145 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ELANE P08246 2/20 0.35
CTSG P08311 1/20 0.35
ALOX5 P09917 2/20 0.35
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
DHFR P00374 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2886031 0.91 ESR1 (0.45) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL20233960 0.89 DHFR (0.41) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL900106 0.88 ESR1 (0.51) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL29842572 0.84 ESR1 (0.60) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL383400 0.84 ESR1 (0.60) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL29632605 0.84 KDM4E (0.47) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL10051848 0.81 ESR1 (0.47) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL19334604 0.81 ESR1 (0.56) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL19843860 0.80 ESR1 (0.55) ESR1ESR2PDK2KDM4EMEN1
SCHEMBL10076748 0.79 ESR1 (0.50) ESR1ESR2PDK2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781540-B2 Resin composition and molded articles thereof OSAKA GAS CO., LTD. (JP) 2010-08-24 US disclosed
US-7772356-B2 Infrared absorption filter OSAKA GAS CO., LTD. (JP) 2010-08-10 US disclosed
US-7645534-B2 Membrane electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2010-01-12 US disclosed
US-20090149625-A1 AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP JSR CORPORATION (JP) 2009-06-11 US disclosed
EP-1808461-B1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF TEIJIN CHEMICALS LTD (JP) 2009-03-11 EP disclosed
EP-2011812-A1 AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP JSR Corporation (JP) 2009-01-07 EP disclosed
US-20080085955-A1 Resin Composition And Molded Articles Thereof OSAKA GAS CO., LTD. (JP) 2008-04-10 US disclosed
US-20070293606-A1 Infrared Absorption Filter OSAKA GAS CO., LTD. (JP) 2007-12-20 US disclosed
US-20070248865-A1 Membrane electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2007-10-25 US disclosed
EP-1808461-A1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF Teijin Chemicals, Ltd. (JP) 2007-07-18 EP disclosed
EP-1804093-A1 INFRARED ABSORBING FILTER OSAKA GAS CO., LTD. (JP) 2007-07-04 EP disclosed
EP-1122746-B1 Composition for film formation and insulating film JSR CORP (JP) 2004-09-22 EP disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149625-A1 AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP AFF2, FGFR1, FUS ESR1 843/4885ESR2 992/4885PDK2 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.