Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 7/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890044 | 1.00 | KIF11 (0.51) | KIF11ARPDK2CYP11B2PGR | |
| SCHEMBL27676186 | 0.81 | S1PR1 (0.42) | KIF11ARCYP11B2 | |
| SCHEMBL28668535 | 0.80 | KIF11 (0.57) | KIF11ARPDK2CYP11B2PGR | |
| SCHEMBL28838142 | 0.80 | ACHE (0.42) | PDK2CYP11B2PGRCYP11B1 | |
| SCHEMBL12295373 | 0.80 | AR (0.63) | KIF11ARPDK2CYP11B2PGR | |
| SCHEMBL28838143 | 0.78 | ACHE (0.43) | ARPDK2CYP11B2CYP11B1 | |
| SCHEMBL4450173 | 0.78 | AR (0.61) | KIF11ARPDK2CYP11B2PGR | |
| SCHEMBL397926 | 0.78 | KIF11 (0.65) | KIF11ARPDK2CYP11B2PGR | |
| SCHEMBL28838150 | 0.78 | MEN1 (0.46) | ARPDK2CYP11B2CYP11B1 | |
| SCHEMBL2371259 | 0.77 | AR (0.47) | KIF11ARPDK2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010575-B | Synthesis method of 2-trifluoromethyl naphthalene derivative | 温州大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-115010575-A | Synthesis method of 2-trifluoromethyl naphthalene derivative | 温州大学 | 2022-09-06 | — | — | CN | disclosed |