SCHEMBL28838440

SCHEMBL28838440

C=CCOCC=C.COC(C)(CC(=O)O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL416276 0.83 CYP2C19 (0.50) CYP2D6TSHRCYP2C19HIF1AHMGCR
SCHEMBL3713463 0.83 CYP2C19 (0.50) CYP2D6TSHRCYP2C19HIF1AHMGCR
SCHEMBL4628158 0.83 CYP2C19 (0.50) CYP2D6TSHRCYP2C19HIF1AHMGCR
Pivalate SCHEMBL9055894 0.77 TDP1 (0.35) CYP2D6TSHRCYP2C19HIF1A
Citric Acid SCHEMBL411716 0.74 ALDH1A1 (0.60) CYP2D6TSHRCYP2C19HIF1AHMGCR
Citric Acid SCHEMBL27874691 0.74 ALDH1A1 (0.54) CYP2D6TSHRCYP2C19HIF1AHMGCR
SCHEMBL3348790 0.74 ALDH1A1 (0.37) CYP2D6TSHRCYP2C19HIF1A
Propionic Acid SCHEMBL3430108 0.71 FFAR3 (0.50) CYP2D6TSHR
SCHEMBL782367 0.71 TSHR (0.37) CYP2D6TSHRCYP2C19HIF1A
Citric Acid SCHEMBL28485608 0.70 ALDH1A1 (0.54) CYP2D6TSHRHMGCRCHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104558422-B Method for preparing thermoplastic cellulose based copolymer 天津工业大学 2017-02-22 CN disclosed