SCHEMBL28838840

SCHEMBL28838840

O=C(O)NC1C2CCN(CC2)C1Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 11/20 0.62
CHRNB2 P17787 9/20 0.62
CHRNA4 P43681 9/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6208322 0.82 CHRNA7 (0.77) CHRNA7CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL6208049 0.81 CHRNA7 (0.76) CHRNA7CHRNB2CHRNA4
SCHEMBL5203589 0.79 TACR1 (0.69) CHRNA7CHRNB2CHRNA4
SCHEMBL373001 0.77 CHRNB2 (1.00) CHRNA7CHRNB2CHRNA4
SCHEMBL372799 0.76 CHRNA7 (1.00) CHRNA7CHRNB2CHRNA4
SCHEMBL2863110 0.75 CHRNA7 (0.68) CHRNA7CHRNB2CHRNA4
SCHEMBL3464432 0.75 CHRNA7 (0.76) CHRNA7CHRNB2CHRNA4
SCHEMBL11277115 0.74 POLB (0.46) CHRNA7CHRNB2CHRNA4
SCHEMBL373208 0.74 CHRNB2 (0.88) CHRNA7CHRNB2CHRNA4
SCHEMBL13240100 0.74 CHRNA7 (0.81) CHRNA7CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901652-A Substituted saturated and unsaturated N-heterocyclic carboxamides and related compounds for the treatment of medical disorders 比亚尔R&D投资股份公司 2022-08-12 CN disclosed