Butyryl-Carnitine

Butyryl-Carnitine

SCHEMBL288391

CCCC(=O)O[C@@H](CC(=O)[O-])C[N+](C)(C)C

nearest known ligand 0.78

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.78
KMT2A Q03164 5/20 0.78
MAPT P10636 4/20 0.78
SLC25A20 O43772 3/20 0.78
TP53 P04637 3/20 0.78
TSHR P16473 3/20 0.78
CYP2D6 P10635 2/20 0.78
CYP2C19 P33261 2/20 0.78
SLC6A5 Q9Y345 2/20 0.78
CYP2C9 P11712 2/20 0.78
HIF1A Q16665 2/20 0.78
KDM4E B2RXH2 1/20 0.78
CYP3A4 P08684 1/20 0.78
NFKB1 P19838 1/20 0.78
THPO P40225 1/20 0.78
HSD17B10 Q99714 1/20 0.78
RECQL P46063 1/20 0.76
CYP1A2 P05177 4/20 0.65
HRH1 P35367 1/20 0.65
MAPK1 P28482 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyryl-Carnitine SCHEMBL886918 1.00 MEN1 (0.78) MEN1KMT2AMAPTSLC25A20TP53
Butyryl-Carnitine SCHEMBL237454 1.00 MEN1 (0.78) MEN1KMT2AMAPTSLC25A20TP53
Butyryl-Carnitine SCHEMBL28712508 0.98 MEN1 (0.76) MEN1KMT2AMAPTSLC25A20TP53
Butyryl-Carnitine SCHEMBL28900550 0.94 MEN1 (0.70) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL7048157 0.91 MEN1 (0.77) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL288262 0.90 MEN1 (0.89) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL886920 0.90 MEN1 (0.89) MEN1KMT2AMAPTSLC25A20TP53
Butyryl-Carnitine SCHEMBL6469306 0.90 MEN1 (0.76) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL8977796 0.89 MEN1 (0.97) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL235082 0.89 MEN1 (0.97) MEN1KMT2AMAPTSLC25A20TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11313866-B2 Method of diagnosing and treating asphyxia INFANDX AG (DE) 2022-04-26 US disclosed
EP-2249161-B1 Method of diagnosing asphyxia INFANDX AG (DE) 2020-05-13 EP disclosed
US-20180011111-A1 Method of Diagnosing and Treating Asphyxia INFANDX AG (DE) 2018-01-11 US disclosed
US-9791459-B2 Method of diagnosing and treating asphyxia INFANDX AG (DE) 2017-10-17 US disclosed
EP-2427773-B1 METHOD OF DIAGNOSING ASPHYXIA INFANDX AG (DE) 2016-07-06 EP disclosed
EP-2449488-B1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES LIFE SCIENCES AG (AT) 2015-01-14 EP disclosed
CN-102943106-A Substrates and internal standards for mass spectroscopy detection PERKINELMER LAS INC 2013-02-27 CN disclosed
US-20120208282-A1 Method For Normalization in Metabolomics Analysis Methods with Endogenous Reference Metabolites. BIOCRATES LIFE SCIENCES AG 2012-08-16 US disclosed
US-20120136581-A1 Method of Diagnosing Asphyxia BIOCRATES LIFE SCIENCES AG (AT) 2012-05-31 US disclosed
EP-2449488-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES Life Sciences AG (AT) 2012-05-09 EP disclosed
EP-2427773-A1 METHOD OF DIAGNOSING ASPHYXIA Keller, Matthias (DE) 2012-03-14 EP disclosed
WO-2011000753-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES LIFE SCIENCES AG (AT) 2011-01-06 WO disclosed
EP-2270699-A1 Method for normalization in metabolomics analysis methods with endogenous reference metabolites BIOCRATES Life Sciences AG (AT) 2011-01-05 EP disclosed
WO-2010128054-A1 METHOD OF DIAGNOSING ASPHYXIA BIOCRATES LIFE SCIENCES AG (AT) 2010-11-11 WO disclosed
CN-101426926-A Substrate and internal standard for mass spectrometry detection PERKINELMER LAS INC (US) 2009-05-06 CN disclosed
EP-1999270-A2 SUBSTRATES AND INTERNAL STANDARDS FOR MASS SPECTROSCOPY DETECTION Perkinelmer Las, Inc. (US) 2008-12-10 EP disclosed
WO-2007106816-A2 SUBSTRATES AND INTERNAL STANDARDS FOR MASS SPECTROSCOPY DETECTION PERKINELMER LAS, INC. (US) 2007-09-20 WO disclosed