Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.70 |
| ▸ | HRH1 | P35367 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | THPO | P40225 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyryl-Carnitine SCHEMBL17847433 | 0.95 | MEN1 (0.68) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Butyryl-Carnitine SCHEMBL288391 | 0.90 | MEN1 (0.78) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Butyryl-Carnitine SCHEMBL886918 | 0.90 | MEN1 (0.78) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Butyryl-Carnitine SCHEMBL237454 | 0.90 | MEN1 (0.78) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Butyryl-Carnitine SCHEMBL28712508 | 0.89 | MEN1 (0.76) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Levocarnitine Propionate SCHEMBL7177881 | 0.88 | MEN1 (0.78) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Propionyl-Carnitine SCHEMBL994714 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Levocarnitine Propionate SCHEMBL464940 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Propionyl-Carnitine SCHEMBL156850 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| Propionyl-Carnitine SCHEMBL6919852 | 0.86 | MEN1 (0.76) | MEN1KMT2ACYP2C19RECQLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198260-B2 | Therapy for metabolism disorders; anticholesterol agents; antilipemic agents; obesity; synergistic mixture | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SPA (IT) | 2012-06-12 | — | — | US | disclosed |
| US-20050020538-A1 | Composition for the prevention and/or treatment of disorders due to abnormal lipid metabolism, comprising propionyl L-carnitine and chitosan | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-01-27 | — | — | US | disclosed |
| US-6780851-B1 | TREATMENT OF DISORDERS DUE TO ABNORMAL LIPID METABOLISM, SUCH AS HYPERCHOLESTEROLAEMIA, ATHEROSCLEROSIS, HYPERLIPIDAEMIA AND OBESITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-08-24 | — | — | US | disclosed |