Butyryl-Carnitine

Butyryl-Carnitine

SCHEMBL886918

CCCC(=O)O[C@H](CC(=O)[O-])C[N+](C)(C)C

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.78
KMT2A Q03164 5/20 0.78
MAPT P10636 4/20 0.78
SLC25A20 O43772 3/20 0.78
TP53 P04637 3/20 0.78
TSHR P16473 3/20 0.78
CYP2D6 P10635 2/20 0.78
CYP2C19 P33261 2/20 0.78
SLC6A5 Q9Y345 2/20 0.78
CYP2C9 P11712 2/20 0.78
HIF1A Q16665 2/20 0.78
KDM4E B2RXH2 1/20 0.78
CYP3A4 P08684 1/20 0.78
NFKB1 P19838 1/20 0.78
THPO P40225 1/20 0.78
HSD17B10 Q99714 1/20 0.78
RECQL P46063 1/20 0.76
CYP1A2 P05177 4/20 0.65
HRH1 P35367 1/20 0.65
MAPK1 P28482 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyryl-Carnitine SCHEMBL288391 1.00 MEN1 (0.78) MEN1KMT2AMAPTSLC25A20TP53
Butyryl-Carnitine SCHEMBL237454 1.00 MEN1 (0.78) MEN1KMT2AMAPTSLC25A20TP53
Butyryl-Carnitine SCHEMBL28712508 0.98 MEN1 (0.76) MEN1KMT2AMAPTSLC25A20TP53
Butyryl-Carnitine SCHEMBL28900550 0.94 MEN1 (0.70) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL7048157 0.91 MEN1 (0.77) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL288262 0.90 MEN1 (0.89) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL886920 0.90 MEN1 (0.89) MEN1KMT2AMAPTSLC25A20TP53
Butyryl-Carnitine SCHEMBL6469306 0.90 MEN1 (0.76) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL8977796 0.89 MEN1 (0.97) MEN1KMT2AMAPTSLC25A20TP53
SCHEMBL235082 0.89 MEN1 (0.97) MEN1KMT2AMAPTSLC25A20TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112986430-B Method for screening difference markers of Juansan milk powder and Holstein milk powder and application thereof 中国农业科学院农业质量标准与检测技术研究所 2022-09-16 CN claimed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US claimed
US-20170199203-A1 METABOLITE PANEL FOR IMPROVED SCREENING AND DIAGNOSTIC TESTING OF CYSTIC FIBROSIS MCMASTER UNIVERSITY (CA) 2017-07-13 US claimed
US-8747906-B2 Dietary supplement enhancing the muscular energy metabolism, comprising an alkanoyl carnitine and ribose SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2014-06-10 US claimed
US-20130309216-A1 DIETARY SUPPLEMENT ENHANCING THE MUSCULAR ENERGY METABOLISM, COMPRISING AN ALKANOYL CARNITINE AND RIBOSE SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2013-11-21 US claimed
US-8207109-B2 Mixture of propionyl carnitine, coenzyme Q10, nicotinamide, riboflavin and pantothenine acid SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SPA (IT) 2012-06-26 US claimed
US-20110313040-A1 ORGANIC NUTRIENT SALTS, METHODS OF PREPARATION AND USES BELLUS HEALTH INC. (CA) 2011-12-22 US claimed
EP-1940251-B1 DIETARY SUPPLEMENT ENERGY-PROVIDING TO SKELETAL MUSCLES AND PROTECTING THE CARDIO VASCULAR TRACT SIGMA TAU IND FARMACEUTI (IT) 2011-11-30 EP claimed
US-8067468-B2 L-carnitine and alkanoyl L-carnitine phytates and process for preparing the same SCIAN LABORATORIES, LLC 2011-11-29 US claimed
JP-2011524415-A 2011-09-01 JP claimed
EP-0983066-A1 PHARMACEUTICAL COMPOSITION COMPRISING ALKANOYL L-CARNITINE IN COMBINATION WITH A STATINE FOR TREATING PATHOLOGIES BROUGHT ABOUT BY AN ALTERED LIPID METABOLISM Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 2000-03-08 EP claimed
WO-2000006134-A2 USE OF L-CARNITINE AND ITS ALKANOYL DERIVATIVES IN THE PREPARATION OF MEDICAMENTS WITH ANTICANCER ACTIVITY SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2000-02-10 WO claimed
WO-1999053921-A1 COMPOSITION COMPRISING L-CARNITINE OR AN ALKANOYL L-CARNITINE AND NADH AND/OR NADPH SIGMA-TAU HEALTHSCIENCE S.P.A. (IT) 1999-10-28 WO claimed
EP-0951909-A1 Combination composition comprising a L-carnitine or an alkanoyl-L-carnitine, a glycosaminoglycan and/or constituent thereof Sigma-Tau Healthscience S.p.A. (IT) 1999-10-27 EP claimed
WO-1999052517-A2 COMPOSITION COMPRISING KETANSERIN AND L-CARNITINE OR AN ALKANOYL L-CARNITINE FOR THE TREATMENT OF CRPS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1999-10-21 WO claimed
US-RE36331-E Use of L-carnitine and alkanoyl L-carnitines in the storage of blood for transfusions and stabilizing solutions containing them SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1999-10-05 US claimed
EP-0722724-B1 Use of L-carnitine and its derivatives for reducing the toxic effects of cyclosporin-A and others immunosuppressants SIGMA TAU IND FARMACEUTI (IT) 1999-03-24 EP claimed
WO-1999006039-A1 COMPOSITION COMPRISING L-CARNITINE OR AN ALKANOYL L-CARNITINE AND LONG-CHAIN ALKANOLS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1999-02-11 WO claimed
WO-1999001126-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING ALKANOYL L-CARNITINE IN COMBINATION WITH A STATINE FOR TREATING PATHOLOGIES BROUGHT ABOUT BY AN ALTERED LIPID METABOLISM SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1999-01-14 WO claimed
US-5496821-A Use of L-carnitine and alkanoyl L-carnitines in the storage of blood for transfusions and stabilizing solutions containing them SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1996-03-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313040-A1 ORGANIC NUTRIENT SALTS, METHODS OF PREPARATION AND USES BDNF, OTC, FABP7 MEN1 2515/4885KMT2A 3011/4885MAPT 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.