Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770353 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1MAPK1ACSS2SPHK1 | |
| SCHEMBL30174466 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1MAPK1ACSS2SPHK1 | |
| SCHEMBL28839349 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1MAPK1ACSS2SPHK1 | |
| SCHEMBL23980750 | 0.88 | PTGER4 (0.52) | ACSS2SPHK1SPHK2PTGER4GLP1R | |
| SCHEMBL29770328 | 0.88 | PTGER4 (0.52) | ACSS2SPHK1SPHK2PTGER4GLP1R | |
| SCHEMBL30020631 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPK1ACSS2PTGER4 | |
| SCHEMBL24900216 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPK1ACSS2PTGER4 | |
| SCHEMBL24900218 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPK1ACSS2PTGER4 | |
| SCHEMBL25005475 | 0.87 | ACSS2 (0.47) | KDM4EALDH1A1MAPK1ACSS2GLP1R | |
| SCHEMBL30680763 | 0.87 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPK1ACSS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907351-A | Tricyclic GLP-1 receptor agonists and uses thereof | 杭州中美华东制药有限公司 | 2022-08-16 | — | — | CN | disclosed |