Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460812 | 0.80 | KCNH2 (0.44) | SIGMAR1EPHX2KMT2ABCHEMEN1 | |
| SCHEMBL5457448 | 0.75 | NCEH1 (0.43) | KMT2A | |
| SCHEMBL28538586 | 0.74 | L3MBTL1 (0.52) | KMT2A | |
| SCHEMBL22364125 | 0.72 | KDM4E (0.61) | KMT2AMEN1 | |
| SCHEMBL20598171 | 0.72 | ALDH1A1 (0.55) | SIGMAR1 | |
| SCHEMBL9578028 | 0.71 | ALDH1A1 (0.42) | KMT2AMEN1 | |
| SCHEMBL22042251 | 0.71 | NCEH1 (0.49) | KMT2A | |
| SCHEMBL10583447 | 0.70 | MAPT (0.40) | KMT2A | |
| SCHEMBL10583442 | 0.70 | KDM4E (0.46) | KMT2A | |
| Hydrogen Peroxide SCHEMBL8610670 | 0.70 | TSHR (0.52) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790173-B | Carbazoles having diaza-dibenzofuran or diaza-dibenzothiophene structure | 默克专利有限公司 | 2022-09-06 | — | — | CN | disclosed |