Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.59 |
| ▸ | KIF11 | P52732 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997852 | 0.86 | KIF11 (0.57) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309607 | 0.84 | LMNA (0.64) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309365 | 0.84 | LMNA (0.61) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309590 | 0.82 | LMNA (0.67) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309927 | 0.82 | POLB (0.66) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309606 | 0.82 | POLB (0.66) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309858 | 0.82 | LMNA (0.66) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309468 | 0.81 | LMNA (0.59) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309737 | 0.80 | MAPT (0.69) | LMNATP53MAPTABCB1ABCG2 | |
| SCHEMBL21309748 | 0.80 | LMNA (0.59) | LMNATP53MAPTABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432237-B | Amidine compound of the one kind containing two chiral centres synthesizes and purposes | 西华大学 | 2017-12-22 | — | — | CN | disclosed |
| CN-106432237-A | Synthesis and purpose of amidine compound containing two chiral centers | 西华大学 | 2017-02-22 | — | — | CN | disclosed |