Morpholine

Morpholine

SCHEMBL28839732

C1COCCN1.OCCO.[SbH3]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
GAA P10253 1/20 0.61
CYP2C9 P11712 1/20 0.61
ALDH1A1 P00352 1/20 0.32
APEX1 P27695 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL27933396 0.97 KDM4E (0.65) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL28011699 0.83 KDM4E (0.55) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL27588949 0.83 KDM4E (0.55) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL1121824 0.82
Morpholine SCHEMBL28279707 0.82 MEN1 (0.61) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL9705438 0.81 MEN1 (0.52) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL28322795 0.81
Morpholine SCHEMBL7996463 0.80 MEN1 (0.92) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL3233209 0.80 MEN1 (0.92) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL18434 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115044026-A Degradable high-barrier uvioresistant bio-based polyester and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-09-13 CN disclosed