SCHEMBL28839780

SCHEMBL28839780

CC(C)(C)OC(=O)N1CC2(F)C([C@H]1CO)C2(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.38
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TACR1 P25103 6/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
HSD17B10 Q99714 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29905516 0.80
SCHEMBL28839653 0.80 HSD17B10 (0.36) CHRM2CHRM1CHRM3HSD17B10
SCHEMBL29770799 0.76 NR1H2 (0.42) NR1H2MEN1KMT2ATACR1CHRM2
SCHEMBL29134449 0.76 NR1H2 (0.42) NR1H2MEN1KMT2ATACR1CHRM2
SCHEMBL13765261 0.74 NR1H2 (0.40) NR1H2MEN1KMT2ACHRM2CHRM1
SCHEMBL13759641 0.74 NR1H2 (0.40) NR1H2MEN1KMT2ATACR1CHRM2
SCHEMBL3885436 0.74 NR1H2 (0.40) NR1H2MEN1KMT2ATACR1CHRM2
SCHEMBL31336719 0.73 NR1H2 (0.38) NR1H2MEN1KMT2ATACR1CHRM2
SCHEMBL7407281 0.71 NR1H2 (0.43) NR1H2MEN1KMT2ACHRM2CHRM1
SCHEMBL29770741 0.71 NR1H2 (0.43) NR1H2MEN1KMT2ACHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115043900-B Peptoid compound and application thereof in preparation of 2019-nCoV main protease inhibitor 深圳博瑞医药科技有限公司 2025-02-18 CN disclosed
CN-115043900-A Peptide-like compound and application thereof in preparation of 2019-nCoV main protease inhibitor 深圳博瑞医药科技有限公司 2022-09-13 CN disclosed