Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336605 | 0.89 | ALDH1A1 (0.32) | NR1H2MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL31336642 | 0.87 | USP2 (0.30) | USP2SMN1; SMN2 | |
| SCHEMBL31336629 | 0.79 | ALDH1A1 (0.35) | TACR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31336643 | 0.77 | KDM4E (0.34) | TACR1MEN1KMT2A | |
| SCHEMBL31716641 | 0.75 | NR1H2 (0.42) | NR1H2TACR1MEN1KMT2AUSP2 | |
| SCHEMBL29134449 | 0.75 | NR1H2 (0.42) | NR1H2TACR1MEN1KMT2AUSP2 | |
| SCHEMBL29770799 | 0.75 | NR1H2 (0.42) | NR1H2TACR1MEN1KMT2AUSP2 | |
| SCHEMBL28839780 | 0.73 | NR1H2 (0.38) | NR1H2TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL13765261 | 0.72 | NR1H2 (0.40) | NR1H2MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL18259601 | 0.72 | USP2 (0.41) | NR1H2USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |