SCHEMBL28839873

SCHEMBL28839873

O=C(CCN1CCOCC1)Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
MAPT P10636 2/20 0.63
KMT2A Q03164 2/20 0.63
LMNA P02545 1/20 0.58
CYP2C19 P33261 1/20 0.58
POLB P06746 2/20 0.55
SIGMAR1 Q99720 1/20 0.55
HSP90AA1 P07900 1/20 0.55
EGFR P00533 1/20 0.54
GLA P06280 1/20 0.53
HTT P42858 2/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
FKBP1A P62942 1/20 0.51
USP2 O75604 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9595976 0.85 CD274 (0.50) ALDH1A1MAPTKMT2ALMNACYP2C19
SCHEMBL3992619 0.84 ALDH1A1 (0.49) ALDH1A1MAPTKMT2ALMNACYP2C19
SCHEMBL8491361 0.84 ALDH1A1 (0.61) ALDH1A1MAPTKMT2ALMNAPOLB
SCHEMBL3997835 0.83 EGFR (0.62) ALDH1A1MAPTKMT2AEGFRHTT
SCHEMBL9199690 0.78 HTT (0.56) ALDH1A1MAPTKMT2ALMNACYP2C19
SCHEMBL321369 0.78 ALDH1A1 (1.00) ALDH1A1MAPTKMT2ALMNACYP2C19
SCHEMBL28005538 0.77 GLA (0.69) ALDH1A1MAPTKMT2ALMNACYP2C19
Hydrochloric Acid SCHEMBL9119984 0.77 ALDH1A1 (0.56) ALDH1A1MAPTKMT2ALMNACYP2C19
SCHEMBL10132932 0.77 EPHX2 (0.63) ALDH1A1KMT2AHTTNPC1RAB9A
SCHEMBL30673257 0.76 ALDH1A1 (0.82) ALDH1A1KMT2ALMNAPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414398-B Compound, active energy ray-curable composition, cured product thereof, printing ink, and ink for inkjet recording DIC株式会社 2019-04-05 CN disclosed
CN-106414398-A Compound, active energy ray-curable composition, cured product thereof, printing ink, and ink for inkjet recording DIC株式会社 2017-02-15 CN disclosed