Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9119984 | 0.99 | ALDH1A1 (0.56) | HTTALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL9120369 | 0.88 | KMT2A (0.60) | HTTALDH1A1KMT2AMAPTGAA | |
| Hydrochloric Acid SCHEMBL9122307 | 0.87 | KMT2A (0.58) | HTTALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL9121156 | 0.87 | KMT2A (0.58) | HTTALDH1A1KMT2AMAPTGAA | |
| SCHEMBL9207862 | 0.87 | KMT2A (0.58) | HTTALDH1A1KMT2AMAPTGAA | |
| Hydrochloric Acid SCHEMBL9120318 | 0.86 | KMT2A (0.57) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL9766005 | 0.79 | HTR1A (0.50) | GAA | |
| SCHEMBL28839873 | 0.78 | ALDH1A1 (0.63) | HTTALDH1A1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL8338610 | 0.77 | KMT2A (0.74) | ALDH1A1KMT2ALMNAMAPTGLA | |
| SCHEMBL5256238 | 0.77 | HTT (0.69) | HTTALDH1A1KMT2ALMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490769-B1 | Aminoalkylketone derivatives, process for their preparation and their therapeutical use | LAFON LABOR (FR) | 1995-04-19 | — | — | EP | disclosed |
| EP-0490769-A1 | Aminoalkylketone derivatives, process for their preparation and their therapeutical use | LABORATOIRE L. LAFON (FR) | 1992-06-17 | — | — | EP | disclosed |