Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863137 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAACYSLTR1PDE10ACYSLTR2 | |
| SCHEMBL30824487 | 0.77 | TSHR (0.41) | CYSLTR1PDE10ACYSLTR2KDM4EGPR3 | |
| SCHEMBL10669295 | 0.76 | CYSLTR1 (0.57) | CYSLTR1PDE10ACYSLTR2GPBAR1SMN1; SMN2 | |
| SCHEMBL9934866 | 0.74 | KDM4E (0.42) | ALDH1A1PDE10AKDM4EGPR3EGFR | |
| SCHEMBL7510557 | 0.72 | CYSLTR1 (0.57) | CYSLTR1PDE10ACYSLTR2CYP1A2ALOX5 | |
| SCHEMBL27706169 | 0.72 | PDE10A (0.58) | ALDH1A1GAACYSLTR1PDE10ACYSLTR2 | |
| SCHEMBL1092433 | 0.72 | PDGFRB (0.46) | ALDH1A1PDE10AKDM4ECYP1A2PDGFRB | |
| SCHEMBL28044580 | 0.72 | KDM4E (0.34) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28931171 | 0.71 | ATM (0.44) | ALDH1A1PDE10AKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL7168931 | 0.71 | SMN1; SMN2 (0.51) | ALDH1A1GAACYSLTR1PDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103797002-B | Dyrk1 inhibitors and uses thereof | 迪亚克森海特公司 | 2017-02-22 | — | — | CN | claimed |
| CN-103797002-B | Dyrk1 inhibitors and uses thereof | 迪亚克森海特公司 | 2017-02-22 | — | — | CN | disclosed |