SCHEMBL2884012

SCHEMBL2884012

CO[Si](CCCSc1ncc[nH]1)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.45
GRIN2B Q13224 2/20 0.39
GRIN2A Q12879 1/20 0.39
TXN P10599 1/20 0.37
TXNRD1 Q16881 1/20 0.37
GPR84 Q9NQS5 1/20 0.34
CYP1A2 P05177 6/20 0.33
CYP3A4 P08684 6/20 0.33
CYP2C9 P11712 6/20 0.33
CYP2C19 P33261 6/20 0.33
CYP2E1 P05181 5/20 0.33
CYP2C8 P10632 5/20 0.33
CYP2D6 P10635 5/20 0.33
CYP2B6 P20813 5/20 0.33
CTSK P43235 1/20 0.33
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2884522 0.87 FDPS (0.42) FDPSGRIN2BGRIN2ATXNTXNRD1
SCHEMBL12572516 0.86 FDPS (0.41) FDPSGRIN2BGRIN2ATXNTXNRD1
SCHEMBL7123551 0.80 GPR84 (0.41) FDPSGRIN2BGRIN2ATXNTXNRD1
SCHEMBL10577072 0.76 FDPS (0.56) FDPSGRIN2BGRIN2ATXNTXNRD1
SCHEMBL6169090 0.76 GPR84 (0.55) FDPSGRIN2BGRIN2ATXNTXNRD1
SCHEMBL11102251 0.75 FDPS (0.49) FDPSGRIN2BGRIN2ATXNTXNRD1
SCHEMBL2880882 0.75 HDAC1 (0.42) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL11330161 0.75 GPR84 (0.58) FDPSTXNTXNRD1GPR84CYP2C9
SCHEMBL17733013 0.74 CYP2C9 (0.36) CYP1A2CYP3A4CYP2C9CYP2C19CYP2E1
SCHEMBL7436412 0.74 FDPS (0.51) FDPSGRIN2BGRIN2ATXNTXNRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7851580-B2 Polymer electrolyte membranes (PEMs) based on imidazole ring terminated flexible branches grafted on hybrid inorganic-organic polymers TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2010-12-14 US disclosed
US-7851580-B2 Polymer electrolyte membranes (PEMs) based on imidazole ring terminated flexible branches grafted on hybrid inorganic-organic polymers TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2010-12-14 US disclosed
US-20070099035-A1 Polymer electrolyte membranes (pems) based on imidazole ring terminated flexible branches grafted on hybrid inorganic-organic polymers TOYOTA MOTOR CORPORATION (JP) 2007-05-03 US disclosed
US-20070099035-A1 Polymer electrolyte membranes (pems) based on imidazole ring terminated flexible branches grafted on hybrid inorganic-organic polymers TOYOTA MOTOR CORPORATION (JP) 2007-05-03 US disclosed