Methacrylic Acid

Methacrylic Acid

SCHEMBL28840208

C=C(C)C(=O)O.CCNCCO

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
CYP2C19 P33261 2/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
POLB P06746 1/20 0.31
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethanolamine SCHEMBL2405576 0.89 TGFBR1 (0.38) TGFBR1MEN1KMT2APOLBALDH1A1
Diethanolamine SCHEMBL7729802 0.89 TGFBR1 (0.38) TGFBR1MEN1KMT2APOLBALDH1A1
Acetic Acid SCHEMBL27210323 0.86 CYP2C19 (0.39) CYP2C19MEN1GLAKMT2ACYP1A2
Acetic Acid SCHEMBL8850209 0.86 CYP2C19 (0.39) CYP2C19MEN1GLAKMT2ACYP1A2
Methacrylic Acid SCHEMBL30732488 0.84 PAOX (0.42) TGFBR1CYP2C19MEN1GLAKMT2A
Acetic Acid SCHEMBL28324458 0.84 CYP2C19 (0.38) CYP2C19MEN1GLAKMT2ACYP1A2
Acetic Acid SCHEMBL28660785 0.84 CYP2C19 (0.38) CYP2C19MEN1GLAKMT2ACYP1A2
Methacrylic Acid SCHEMBL5514685 0.84 TP53 (0.44) TGFBR1TSHRALDH1A1ALOX15
Acetic Acid SCHEMBL7158387 0.82 CYP2C19 (0.42) CYP2C19MEN1GLAKMT2ACYP1A2
Bicarbonate SCHEMBL28204460 0.81 CYP2C19 (0.39) CYP2C19MEN1GLAKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104284918-B urethane type and urea ester type compound and preparation method thereof 高剑萍 2017-03-29 CN claimed