Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 11/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898774 | 0.85 | SCN4A (0.38) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL27986956 | 0.81 | S1PR1 (0.43) | CYP1A2TSHRGLAMAPT | |
| SCHEMBL27931937 | 0.79 | SCN9A (0.38) | SCN9AMAPT | |
| SCHEMBL4550431 | 0.78 | SCN4A (0.46) | SCN4ARXRAPPARGRARGLMNA | |
| SCHEMBL28840247 | 0.77 | SCN4A (0.37) | SCN4ARXRAPPARGRARGRARB | |
| SCHEMBL2714089 | 0.77 | POLB (0.38) | SCN4ARXRAPPARGRARGRARB | |
| Hydrochloric Acid SCHEMBL2716056 | 0.77 | SCN5A (0.46) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL2716010 | 0.77 | TPMT (0.39) | SCN4ACYP1A2 | |
| SCHEMBL27986840 | 0.75 | APP (0.38) | PPARG | |
| SCHEMBL19664495 | 0.75 | GLA (0.47) | SCN4ALMNASCN1ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478497-A | Aryl amine derivatives as TTX S blocker | 拉夸里亚创药株式会社 | 2017-03-08 | — | — | CN | disclosed |