Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 13/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550431 | 0.78 | SCN4A (0.46) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL28840246 | 0.77 | SCN4A (0.37) | SCN4ALMNASCN1ASCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL2716056 | 0.77 | SCN5A (0.46) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL27986841 | 0.75 | PPARG (0.34) | PPARG | |
| SCHEMBL19664495 | 0.75 | GLA (0.47) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL27914049 | 0.70 | SCN4A (0.39) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL2714089 | 0.70 | POLB (0.38) | SCN4ALMNARXRAPPARGRARG | |
| SCHEMBL2716010 | 0.70 | TPMT (0.39) | SCN4ACYP1A2 | |
| SCHEMBL2715708 | 0.69 | SCN4A (0.41) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL4550829 | 0.69 | SCN4A (0.45) | SCN4ALMNASCN1ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478497-A | Aryl amine derivatives as TTX S blocker | 拉夸里亚创药株式会社 | 2017-03-08 | — | — | CN | disclosed |