Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | FLT1 | P17948 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30277951 | 0.82 | NPC1 (0.67) | FGFR1FLT1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL717809 | 0.82 | NPC1 (0.67) | FGFR1FLT1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL30860691 | 0.79 | KDM4E (0.60) | FGFR1FLT1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL147654 | 0.79 | KDM4E (0.60) | FGFR1FLT1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL15524854 | 0.78 | NPC1 (0.55) | FGFR1FLT1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL4115108 | 0.75 | FGFR1 (0.58) | FGFR1FLT1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL30634854 | 0.75 | NPC1 (1.00) | RAB9AKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL30561047 | 0.75 | NPC1 (1.00) | RAB9AKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL172216 | 0.75 | NPC1 (1.00) | RAB9AKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3075421 | 0.75 | ADORA2A (0.75) | RAB9AKDM4ESMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349244-A | Benzo imidazo quinazoline dimethyl oxygen benzene oxygen acetyl-AA-OBzl, as well as synthesis, activity and application thereof | 首都医科大学 | 2017-01-25 | — | — | CN | claimed |