Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.58 |
| ▸ | FLT1 | P17948 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | NPC1 | O15118 | 10/20 | 0.56 |
| ▸ | RAB9A | P51151 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30277951 | 0.81 | NPC1 (0.67) | FGFR1FLT1ALDH1A1NPC1RAB9A | |
| SCHEMBL717809 | 0.81 | NPC1 (0.67) | FGFR1FLT1ALDH1A1NPC1RAB9A | |
| SCHEMBL28840317 | 0.75 | FGFR1 (0.59) | FGFR1FLT1ALDH1A1NPC1RAB9A | |
| SCHEMBL30634854 | 0.74 | NPC1 (1.00) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL30561047 | 0.74 | NPC1 (1.00) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL172216 | 0.74 | NPC1 (1.00) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL311148 | 0.73 | FGFR1 (1.00) | FGFR1FLT1ALDH1A1NPC1RAB9A | |
| SCHEMBL29714859 | 0.73 | FGFR1 (1.00) | FGFR1FLT1ALDH1A1NPC1RAB9A | |
| Water SCHEMBL9817804 | 0.72 | NPC1 (0.95) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28116783 | 0.72 | NPC1 (0.72) | FGFR1FLT1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061796-A2 | AZETIDINE AND AZETIDINONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM | SCHERING CORPORATION (US) | 2009-05-27 | — | — | EP | claimed |
| WO-2008033468-A2 | AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | claimed |
| EP-0160256-A2 | Condensed furanones, process for their preparation and their pharmaceutical use | BAYER AG (DE) | 1985-11-06 | — | — | EP | claimed |
| US-6906121-B2 | 4-nitrosodiphenylamine derivatives and their use as coupling agents for filled rubber compounds | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2005-06-14 | — | — | US | disclosed |