Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.58 |
| ▸ | FLT1 | P17948 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | METAP2 | P50579 | 2/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | METAP1 | P53582 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860691 | 1.00 | KDM4E (0.60) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5066563 | 0.83 | FGFR1 (0.48) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5819055 | 0.79 | FGFR1 (0.53) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL28840317 | 0.79 | FGFR1 (0.59) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL29639097 | 0.79 | F10 (0.65) | — | |
| SCHEMBL6161364 | 0.79 | F10 (0.54) | — | |
| SCHEMBL717809 | 0.78 | NPC1 (0.67) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL30277951 | 0.78 | NPC1 (0.67) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1900287 | 0.75 | NPC1 (0.58) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL29858384 | 0.75 | NPC1 (1.00) | KDM4ENPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793437-B | 3-Coordinated copper (I) -carbene complexes | 南加利福尼亚大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-108299510-B | Iridium complex containing aza-arene auxiliary ligand and preparation method and application thereof | 南京工业大学 | 2020-06-05 | — | — | CN | disclosed |
| US-9773986-B2 | Copper(I)-carbene complexes and organic electroluminescent devices | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-09-26 | — | — | US | disclosed |
| EP-2501707-B1 | 3-COORDINATE COPPER (I) - CARBENE COMPLEXES | UNIV SOUTHERN CALIFORNIA (US) | 2017-08-02 | — | — | EP | disclosed |
| US-20140125221-A1 | 3-COORDINATE COPPER(I)-CARBENE COMPLEXES | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-05-08 | — | — | US | disclosed |
| US-8580394-B2 | 3-coordinate copper(I)-carbene complexes | UNIVERSAL DISPLAY CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| EP-2595482-A1 | ALDOSTERONE SYNTHASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-05-29 | — | — | EP | disclosed |
| EP-2501707-A1 | 3-COORDINATE COPPER (I) - CARBENE COMPLEXES | The University Of Southern California (US) | 2012-09-26 | — | — | EP | disclosed |
| US-20120056529-A1 | 3-COORDINATE COPPER(I)-CARBENE COMPLEXES | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2012012478-A1 | ALDOSTERONE SYNTHASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-01-26 | — | — | WO | disclosed |
| WO-2011063083-A1 | 3-COORDINATE COPPER (I) - CARBENE COMPLEXES | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120056529-A1 | 3-COORDINATE COPPER(I)-CARBENE COMPLEXES | AOC3, AOC2, OCIAD1 | KDM4E 4846/4885NPC1 1221/4885RAB9A 3008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.