Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840755 | 0.98 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL28840800 | 0.95 | BACE1 (0.41) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL28840838 | 0.92 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL30148868 | 0.85 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL28922769 | 0.85 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL30148835 | 0.82 | BACE1 (0.41) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL16995784 | 0.78 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL17675420 | 0.75 | TDP2 (0.37) | BACE1AHRKDM1A | |
| SCHEMBL28840831 | 0.73 | BACE1 (0.39) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL28841078 | 0.73 | AKR1B1 (0.41) | LMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907389-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-08-16 | — | — | CN | disclosed |