Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922769 | 1.00 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL30148835 | 0.97 | BACE1 (0.41) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL16995784 | 0.93 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL28840755 | 0.87 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL28840720 | 0.85 | BACE1 (0.37) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL28840800 | 0.83 | BACE1 (0.41) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL28840838 | 0.79 | BACE1 (0.38) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL4468522 | 0.77 | ENTPD5 (0.40) | MAPT | |
| SCHEMBL1758994 | 0.73 | LMNA (0.40) | BACE1LMNAMAPTHTTBLM | |
| SCHEMBL17675420 | 0.73 | TDP2 (0.37) | BACE1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521325-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-12-27 | — | — | CN | disclosed |