Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208264 | 0.87 | KMT2A (0.47) | TDP1L3MBTL1GLAPOLBPTGES | |
| SCHEMBL9205464 | 0.83 | L3MBTL1 (0.48) | TDP1L3MBTL1GLAPOLBPPARG | |
| SCHEMBL5695124 | 0.83 | KDM4E (0.55) | TDP1L3MBTL1POLBPTGESALOX5 | |
| SCHEMBL5695131 | 0.83 | TSHR (0.53) | TDP1L3MBTL1TSHRCA2ALDH1A1 | |
| SCHEMBL11755152 | 0.82 | TDP1 (0.42) | TDP1POLBPTGESALOX5PPARG | |
| SCHEMBL5695176 | 0.81 | TSHR (0.46) | TDP1L3MBTL1TSHRCA2ALDH1A1 | |
| SCHEMBL5210592 | 0.81 | TDP1 (0.54) | TDP1L3MBTL1POLBPTGESALOX5 | |
| SCHEMBL9202605 | 0.80 | PPARG (0.50) | L3MBTL1GLAPOLBPPARG | |
| SCHEMBL6035268 | 0.80 | TSHR (0.51) | TDP1L3MBTL1POLBTSHRCA2 | |
| SCHEMBL6035267 | 0.80 | KDM4E (0.53) | TDP1L3MBTL1POLBTSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907345-A | Piperidine-benzodiazepine compound having anti-proliferative activity | 福姆通格尼克斯有限公司 | 2022-08-16 | — | — | CN | disclosed |