Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861410 | 0.93 | L3MBTL1 (0.49) | L3MBTL1PPARGPPARATDP1PTGES | |
| SCHEMBL9205464 | 0.92 | L3MBTL1 (0.48) | KMT2AL3MBTL1GLAPPARGPPARA | |
| SCHEMBL28840979 | 0.87 | TDP1 (0.48) | KMT2AL3MBTL1GLAPPARGTDP1 | |
| SCHEMBL9202605 | 0.84 | PPARG (0.50) | L3MBTL1GLAPPARGPPARAMRGPRX4 | |
| SCHEMBL9207231 | 0.82 | ACE (0.47) | KMT2APPARGPPARASMN1; SMN2NPSR1 | |
| SCHEMBL7854550 | 0.80 | PPARG (0.46) | L3MBTL1PPARGPPARATDP1PTGES | |
| SCHEMBL10503384 | 0.79 | SMN1; SMN2 (0.46) | PPARGPPARATDP1PTGESALOX5 | |
| SCHEMBL1859515 | 0.79 | SMN1; SMN2 (0.46) | L3MBTL1PPARGPPARATDP1ALOX5 | |
| SCHEMBL7860020 | 0.76 | L3MBTL1 (0.53) | L3MBTL1PPARGPPARATDP1SMN1; SMN2 | |
| SCHEMBL6714506 | 0.76 | TDP1 (0.65) | KMT2AL3MBTL1TDP1ALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| CN-1028100-C | Process for preparing phenoxy-heterocyclic compounds | MIDICINE INST CHINESE MEDICAL (CN) | 1995-04-05 | — | — | CN | disclosed |
| US-5134154-A | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-28 | — | — | US | disclosed |
| CN-1051039-A | Phenoxy group-heterogeneous ring compound | MERRELL DOW PHARMA (US) | 1991-05-01 | — | — | CN | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |