Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 8/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206911 | 0.79 | ADRA2A (0.38) | CYP1A2SMN1; SMN2CRBNADRA2AADRA2B | |
| SCHEMBL247150 | 0.79 | CRBN (0.50) | CYP1A2SMN1; SMN2CRBNGSK3BNPC1 | |
| Hydrochloric Acid SCHEMBL30515324 | 0.77 | CRBN (0.49) | CYP1A2SMN1; SMN2CRBNADRA2AADRA2B | |
| SCHEMBL19461351 | 0.74 | CYP1A2 (0.42) | CYP1A2SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL1093770 | 0.72 | MAPT (0.53) | CYP1A2SMN1; SMN2CRBNADRA2AADRA2B | |
| SCHEMBL6001078 | 0.72 | PDPK1 (0.42) | CYP1A2SMN1; SMN2CRBNADRA2AADRA2B | |
| SCHEMBL17881248 | 0.72 | CRBN (0.40) | CRBNIDH1GSK3B | |
| SCHEMBL15985267 | 0.72 | NPC1 (0.50) | CYP1A2SMN1; SMN2IDH1MAPTNPC1 | |
| SCHEMBL3964273 | 0.70 | ADRA2A (0.43) | CYP1A2SMN1; SMN2CRBNADRA2AADRA2B | |
| SCHEMBL9755377 | 0.70 | CYP1A2 (0.36) | CYP1A2SMN1; SMN2CRBNADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855294-B2 | Cycloalkanopyridine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-20070191419-A1 | Cycloalkanopyridine derivative | MSD K.K. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1726590-A1 | CYCLOALKANOPYRIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191419-A1 | Cycloalkanopyridine derivative | OPRL1, OPRK1, AVPR2 | CYP1A2 3690/4885SMN1; SMN2 1453/4885CRBN 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.