SCHEMBL28841925

SCHEMBL28841925

CC(=O)OC(=O)CC(F)(F)F.CC(=O)OC(=O)CC(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25285348 0.88 HTT (0.31)
SCHEMBL28841924 0.88 HTT (0.31)
SCHEMBL2306829 0.86 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL801 0.86 ALDH1A1 (0.43) ALDH1A1TSHR
Methylene Chloride SCHEMBL28135451 0.80 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL800 0.72 ALDH1A1 (0.35) ALDH1A1
SCHEMBL776389 0.72 ALDH1A1 (0.35) ALDH1A1
SCHEMBL25236407 0.71
SCHEMBL25235390 0.71 HTT (0.39)
SCHEMBL25240582 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106928247-A Spiral shell oxindole compounds and its purposes as therapeutic agent 泽农医药公司 2017-07-07 CN disclosed
CN-103664973-B Spiro-oxindole compounds and their use as therapeutic agents 泽农医药公司 2017-04-19 CN disclosed
CN-102256983-B Spirooxindole compounds and their use as therapeutic agents 泽农医药公司 2017-04-05 CN disclosed