Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17512467 | 0.79 | GABRP (0.40) | HCAR2KDM4EGABRA1GABRG2GABRB3 | |
| SCHEMBL28636839 | 0.74 | FBP1 (0.40) | HCAR2KDM4ETSHRTDP1POLB | |
| SCHEMBL15527495 | 0.74 | TSHR (0.34) | HCAR2PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1284339 | 0.74 | TDP1 (0.37) | HCAR2CYP1A2HIF1AKDM4EGABRA1 | |
| SCHEMBL29065888 | 0.73 | KDM4E (0.37) | HCAR2KDM4EGABRA1GABRG2GABRB3 | |
| SCHEMBL29771512 | 0.72 | HSD17B10 (0.41) | KDM4ETSHRHSD17B10KMOGPR35 | |
| SCHEMBL22890254 | 0.72 | HSD17B10 (0.41) | KDM4ETSHRHSD17B10KMOGPR35 | |
| SCHEMBL15527867 | 0.72 | GABRP (0.33) | HCAR2PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18893724 | 0.72 | HSD17B10 (0.34) | HCAR2RXFP1KDM4ETSHRHSD17B10 | |
| SCHEMBL17732158 | 0.72 | HCAR2 (0.33) | HCAR2KDM4ETSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183449-B | Mnk inhibitors and methods related thereto | 效应治疗股份有限公司 | 2022-08-19 | — | — | CN | disclosed |