Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721708 | 0.90 | PDE4B (0.36) | NR1H2HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL4772238 | 0.86 | KMT2A (0.38) | NR1H2HPGDKMT2AMEN1RECQL | |
| SCHEMBL28556370 | 0.80 | NR1H2 (0.33) | NR1H2ABCB1 | |
| SCHEMBL28428311 | 0.79 | CHRM2 (0.39) | NR1H2HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL28107442 | 0.79 | USP2 (0.37) | NR1H2HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL30121408 | 0.77 | CHRM2 (0.34) | NR1H2HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL19892750 | 0.77 | CHRM2 (0.34) | NR1H2HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL27510719 | 0.73 | CTSK (0.33) | NR1H2CHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL28102330 | 0.72 | LMNA (0.36) | NR1H2CHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL20545175 | 0.71 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115103709-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2022-09-23 | — | — | CN | disclosed |