Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27340414 | 0.81 | LOXL2 (0.46) | HRH3TAAR1AKT2LOXL2ADRB2 | |
| SCHEMBL28200610 | 0.77 | AKT2 (0.40) | HRH3TAAR1AKT2LOXL2ADRB2 | |
| SCHEMBL2274647 | 0.76 | HRH3 (1.00) | HRH3TAAR1LOXL2ADRB2ASIC3 | |
| SCHEMBL28089504 | 0.75 | TAAR1 (0.68) | HRH3TAAR1AKT2LOXL2ADRB2 | |
| SCHEMBL15111980 | 0.73 | HRH3 (0.61) | HRH3TAAR1AKT2LOXL2ADRB2 | |
| SCHEMBL27238704 | 0.72 | HRH3 (0.79) | HRH3TAAR1LOXL2ADRB2ABAT | |
| SCHEMBL15828 | 0.72 | HRH3 (0.79) | HRH3TAAR1LOXL2ADRB2ABAT | |
| SCHEMBL5362598 | 0.71 | TAAR1 (0.77) | HRH3TAAR1LOXL2ADRB2LTA4H | |
| SCHEMBL28956611 | 0.71 | HRH3 (0.59) | HRH3TAAR1AKT2LOXL2ADRB2 | |
| SCHEMBL11347769 | 0.70 | HRH3 (0.74) | HRH3TAAR1LOXL2ADRB2ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565584-A | Preparing method for 3,4-bis(4-bromophenyl)-1H-pyrrole-2,5-diketone | 东华大学 | 2017-04-19 | — | — | CN | disclosed |