SCHEMBL28842802

SCHEMBL28842802

NC(=O)CC(OC=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.46
CYP1A2 P05177 1/20 0.46
PKM P14618 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CYP2C19 P33261 3/20 0.45
ALDH1A1 P00352 1/20 0.42
SLC6A3 Q01959 3/20 0.41
DRD3 P35462 2/20 0.41
LMNA P02545 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
EDNRB P24530 1/20 0.41
MAPK1 P28482 1/20 0.41
MC4R P32245 1/20 0.41
MC3R P41968 1/20 0.41
DRD2 P14416 1/20 0.41
GABBR2 O75899 1/20 0.40
GABBR1 Q9UBS5 1/20 0.40
GLS O94925 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12530084 0.86 GABBR2 (0.46) CYP2D6SMN1; SMN2CYP2C19GABBR2GABBR1
SCHEMBL12530277 0.86 GABBR2 (0.46) CYP2D6SMN1; SMN2CYP2C19GABBR2GABBR1
SCHEMBL7394971 0.86 GABBR2 (0.46) CYP2D6SMN1; SMN2CYP2C19GABBR2GABBR1
SCHEMBL14210525 0.83 KMT2A (0.42) CYP2D6ALDH1A1GLSL3MBTL1KMT2A
SCHEMBL16416740 0.80 CYP2D6 (0.44) CYP2D6CYP1A2PKMSMN1; SMN2NPSR1
SCHEMBL4780750 0.79 ALDH1A1 (0.51) CYP2D6CYP1A2PKMSMN1; SMN2NPSR1
SCHEMBL27280983 0.78 TAAR1 (0.46) SLC6A3GABBR2GABBR1
SCHEMBL14233222 0.78 TSHR (0.47) CYP2D6SMN1; SMN2CYP2C19ALDH1A1LMNA
SCHEMBL13506682 0.76 FFAR1 (0.49) CYP2D6CYP1A2PKMSMN1; SMN2NPSR1
SCHEMBL7330797 0.76 CYP1A2 (0.46) CYP2D6CYP1A2PKMSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115040458-A Anti-wrinkle composition and preparation method and application thereof 广州安若希医药科技有限公司 2022-09-13 CN disclosed