Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYCS | P99999 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703878 | 0.94 | TERT (0.37) | CHEK1WEE1MAPTKDM4EMEN1 | |
| SCHEMBL14701518 | 0.90 | ABCG2 (0.36) | CHEK1WEE1MAPTKDM4ENPC1 | |
| SCHEMBL30081962 | 0.79 | TERT (0.49) | MAPTKDM4EMEN1NPC1RAB9A | |
| SCHEMBL433807 | 0.79 | TERT (0.49) | MAPTKDM4EMEN1NPC1RAB9A | |
| SCHEMBL14703875 | 0.78 | TERT (0.37) | CHEK1WEE1CYCSGRIN2DGRIN3B | |
| SCHEMBL14703826 | 0.78 | KDM4E (0.38) | CHEK1WEE1MAPTKDM4ECYCS | |
| SCHEMBL14703912 | 0.74 | KDM4E (0.38) | CHEK1WEE1MAPTKDM4EMEN1 | |
| SCHEMBL14701515 | 0.74 | ORAI1 (0.38) | KDM4ENPC1RAB9ACYCSTP53 | |
| SCHEMBL14703879 | 0.74 | GCGR (0.41) | CYCSGRIN1GRIN2A | |
| SCHEMBL17166508 | 0.74 | GCGR (0.41) | CYCSGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097390-B | β functionalization dihydroxy chlorin is used for the application of PDT | 拜欧利泰克投资二代公司 | 2017-03-08 | — | — | CN | disclosed |