Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | CYCS | P99999 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703878 | 0.95 | TERT (0.37) | ABCG2PIN1TERTCYCSMAPT | |
| Phenol SCHEMBL28843014 | 0.90 | CHEK1 (0.37) | PIN1TP53CYCSMAPTCHEK1 | |
| SCHEMBL14701515 | 0.85 | ORAI1 (0.38) | ABCG2PIN1TERTACHETP53 | |
| SCHEMBL14701517 | 0.84 | KDM4E (0.39) | ABCG2PIN1TERTTP53TDP1 | |
| SCHEMBL17166280 | 0.81 | GCGR (0.40) | ABCG2TDP1CYCSNPC1RAB9A | |
| SCHEMBL14701519 | 0.81 | GCGR (0.40) | ABCG2TDP1CYCSNPC1RAB9A | |
| SCHEMBL30081962 | 0.80 | TERT (0.49) | ABCG2TERTMAPTNPC1RAB9A | |
| SCHEMBL433807 | 0.80 | TERT (0.49) | ABCG2TERTMAPTNPC1RAB9A | |
| SCHEMBL14703875 | 0.79 | TERT (0.37) | ABCG2PIN1TERTCYCSCHEK1 | |
| SCHEMBL14701511 | 0.79 | ABCG2 (0.39) | ABCG2PIN1TERTACHETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156849-B2 | Application of β-functionalized dihydroxy-chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2015-10-13 | — | — | US | disclosed |
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | TK1, DHPS, DLD | ABCG2 1881/4885PIN1 181/4885TERT 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.