Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28843260 | 1.00 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9AGRM2 | |
| SCHEMBL8789320 | 0.88 | GRM2 (0.43) | MEN1KMT2AGRM2MAPTGAA | |
| SCHEMBL29616873 | 0.79 | BRD4 (0.50) | MEN1KMT2ANPC1RAB9AGRM2 | |
| SCHEMBL28736921 | 0.79 | BRD4 (0.50) | MEN1KMT2ANPC1RAB9AGRM2 | |
| SCHEMBL28736916 | 0.79 | BRD4 (0.50) | MEN1KMT2ANPC1RAB9AGRM2 | |
| SCHEMBL13413551 | 0.77 | BRD4 (0.49) | MEN1KMT2ASMN1; SMN2BRD4 | |
| SCHEMBL20794403 | 0.77 | BRD4 (0.49) | MEN1KMT2ASMN1; SMN2BRD4 | |
| SCHEMBL27998767 | 0.75 | OPRL1 (0.47) | — | |
| SCHEMBL11666707 | 0.74 | HPGD (0.39) | RAB9AUSP2HPGDSMN1; SMN2BRD4 | |
| SCHEMBL8571522 | 0.73 | CTSG (0.36) | GRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075150-B | Method for preparing chiral amino alcohol derivative by asymmetric hydrocarbon bond amination under nonmetal catalysis | 浙江大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-114075150-A | Method for preparing chiral amino alcohol derivative through nonmetal-catalyzed asymmetric carbon-hydrogen bond amination | 浙江大学 | 2022-02-22 | — | — | CN | disclosed |