Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736921 | 1.00 | BRD4 (0.50) | BRD4MEN1KMT2ANPC1KDM4E | |
| SCHEMBL28736916 | 1.00 | BRD4 (0.50) | BRD4MEN1KMT2ANPC1KDM4E | |
| SCHEMBL28843263 | 0.79 | MEN1 (0.45) | BRD4MEN1KMT2ANPC1KDM4E | |
| SCHEMBL28843260 | 0.79 | MEN1 (0.45) | BRD4MEN1KMT2ANPC1KDM4E | |
| SCHEMBL28736910 | 0.78 | BRD4 (0.59) | BRD4MEN1KMT2ANPC1KDM4E | |
| SCHEMBL28736905 | 0.78 | BRD4 (0.59) | BRD4MEN1KMT2ANPC1KDM4E | |
| SCHEMBL29616852 | 0.78 | BRD4 (0.59) | BRD4MEN1KMT2ANPC1KDM4E | |
| SCHEMBL10949669 | 0.78 | ALOX5 (0.45) | BRD4MAPTGAAALDH1A1CHRM1 | |
| SCHEMBL28736912 | 0.74 | BRD4 (0.51) | BRD4MEN1KMT2ANPC1KDM4E | |
| SCHEMBL28736909 | 0.74 | BRD4 (0.51) | BRD4MEN1KMT2ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478405-B | Preparation method of chiral nitrogen substituted tetrahydroquinoxaline | 中国科学院成都生物研究所 | 2023-08-15 | — | — | CN | disclosed |
| CN-114478405-A | Preparation method of chiral nitrogen substituted tetrahydroquinoxaline | 中国科学院成都生物研究所 | 2022-05-13 | — | — | CN | disclosed |