Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 4/20 | 0.60 |
| ▸ | CA9 | Q16790 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28143420 | 0.89 | CA12 (0.66) | KDM4EHPGDMEN1KMT2ATDP1 | |
| SCHEMBL5396825 | 0.83 | NQO1 (0.67) | KDM4EHPGDMEN1KMT2ATDP1 | |
| SCHEMBL5398907 | 0.79 | NQO1 (0.53) | KDM4EHPGDMEN1KMT2ATDP1 | |
| SCHEMBL722615 | 0.77 | HPGD (1.00) | KDM4EHPGDMEN1KMT2ATDP1 | |
| SCHEMBL471860 | 0.76 | NMUR2 (0.68) | KDM4EHPGDMEN1KMT2ATDP1 | |
| 4-Hydroxycoumarins SCHEMBL29452306 | 0.76 | CA12 (1.00) | KDM4EHPGDMEN1KMT2ACYP3A4 | |
| 4-Hydroxycoumarins SCHEMBL29624435 | 0.76 | CA12 (1.00) | KDM4EHPGDMEN1KMT2ACYP3A4 | |
| 4-Hydroxycoumarins SCHEMBL131312 | 0.76 | CA12 (1.00) | KDM4EHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL28227416 | 0.76 | CA12 (0.70) | KDM4EHPGDMEN1KMT2ATDP1 | |
| SCHEMBL30228412 | 0.76 | KCNA3 (0.62) | KDM4EHPGDMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106619686-A | Western medicine for treating bronchiectasis | 郑州仁宏医药科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106491853-A | A kind of Chinese medicine and western medicine combination for treating bronchiectasiss and preparation method thereof | 郑州仁宏医药科技有限公司 | 2017-03-15 | — | — | CN | claimed |